Biological Methods

This page has a list of publications and news articles related to Innovative Strategies - Biological Methods. Find more information on Innovation in HEI's research programs.

Research Report 215
Manabu Shiraiwa
Ting Fang
Jinlai Wei
Pascale SJ Lakey
Brian CH Hwang
Kasey C Edwards
et al.
2023

This report presents the findings of a study led by Manabu Shiraiwa of the University of California, Irvine, a recipient of HEI’s Walter A. Rosenblith New Investigator Award. Shiraiwa and colleagues evaluated the mechanisms of aerosol-induced reactive oxygen species formation by two pathways in the respiratory tract: by chemical reactions  and by immune cells called macrophages.

Study evaluates mechanisms of lung injury by ozone

March 30, 2021

HEI has published Research Report 204, Novel Mechanisms of Ozone-Induced Pulmonary Inflammation and Resolution, and the Potential Protective Role of Scavenger Receptor BI, presenting a study led by Dr. Kymberly Gowdy of East Carolina University (now at Ohio State University).

Research Report 204
Kymberly Gowdy
Brita Kilburg-Basnyat
Myles X Hodge
Sky W Reece
Valery Yermalitsky
Sean S Davies
Jonathan Manke
Michael L Armstrong
Nichole Reisdorph
Robert M Tighe
S Raza Shaikh
2021

Research Report 204 presents a study led by Dr. Kymberly Gowdy of East Carolina University (now at Ohio State University) and colleagues in which they evaluated how acute exposure of mice to ozone affects initiation and resolution of the inflammatory response in the lung.

Summer 2020 Update now available

August 17, 2020

In the new issue of Update, read about two new HEI Board members; HEI’s formal response to EPA’s proposed transparency rule; a new chair for our Review Committee; HEI’s actions to promote diversity; a recently published Walter A. Rosenblith New Investigator report on novel techniques to study VOC–ozone effects… and more!

Newsletter
Health Effects Institute
2020

In this issue of Update, read about two new HEI Board members; HEI’s formal response to EPA’s proposed transparency rule; a new chair for our Review Committee; HEI’s actions to promote diversity; a recently published Walter A. Rosenblith New Investigator report on novel techniques to study VOC–ozone effects… and more!

New HEI report examines pollutant effects on lung cells

July 28, 2020

HEI has published Research Report 201, Understanding the Functional Impact of VOC–Ozone Mixtures on the Chemistry of RNA in Epithelial Lung Cells, led by Dr. Lydia Contreras at the University of Texas, Austin.

Research Report 201
Lydia M Contreras
Juan C Gonzalez-Rivera
Kevin C Baldridge
Dongyu S Wang
Jamie CL Chuvalo-Abraham
Lea Hildebrandt Ruiz
2020

Research Report 201 presents a study led by Dr. Lydia Contreras at the University of Texas, Austin, who is a recipient of HEI’s Walter A. Rosenblith New Investigator Award. Dr. Contreras and colleagues evaluated how exposure of lung cells to volatile organic compounds plus ozone affects oxidation of ribonucleic acid, a key component of cells. The study aimed to improve understanding of the biological mechanisms by which air pollutants can cause effects in human health, thereby expanding our knowledge of potential causal links between exposure and health.

Two new Rosenblith Awardees selected for 2019

December 17, 2019

HEI is pleased to announce that the recipients of the 2019 Walter A. Rosenblith New Investigator Award are Tanya Alderete, assistant professor of epidemiology at the University of Colorado, and Megan Herting, assistant professor of epidemiology at the University of Southern California in Los Angeles (USC).

Walter A. Rosenblith New Investigator Award announced

October 31, 2018

Manabu Shiraiwa, who was recently promoted to associate professor in the Department of Chemistry at the University of California, Irvine, was selected to receive HEI’s 2018 Walter A. Rosenblith New Investigator Award for his proposal “Formation of Reactive Oxygen Species by Organic Aerosols and Transition Metals in Epithelial Lining Fluid.”