Particulate Matter

This report presents the findings of a study led by Manabu Shiraiwa of the University of California, Irvine, a recipient of HEI’s Walter A. Rosenblith New Investigator Award. Shiraiwa and colleagues evaluated the mechanisms of aerosol-induced reactive oxygen species formation by two pathways in the respiratory tract: by chemical reactions  and by immune cells called macrophages.

This study by Dr. George S. Downward and Dr. Roel Vermeulen from Utrecht University, the Netherlands, addresses a clear research gap by leveraging harmonized data from the Asia Cohort Consortium, a large multicenter collaborative research effort in Asia that began in 2008.